内科 裴 紀堯

周術期の血糖管理は強化イ ンスリン療法を原則とし、退院時には各病態に応じてインスリン1日2回投与や経口薬などにより通院加療へと移行します。

主要学歴・勤務歴

平成6年

近畿大学医学部医学科 首席卒業

平成12年

近畿大学大学院医学研究科内科学系専攻 修了

平成14年

近畿大学医学部附属病院内分泌代謝糖尿病内科 病院講師

平成14年9月から現職

所属団体

特記事項

受賞歴

平成6年

近畿大学総長賞

平成12年

東洋紡百周年記念バイオテクノロジー研究財団海外学会発表研究助成

平成14年

近畿大学医学会賞

専門領域

外来担当

論文業績

Multiple endocrine neoplasia type 1 presenting as psychosis.
Shinsuke Kito, Toru Nakajima, Hiroshi Yamadera, Yoshihiko Koga, Shinji Kosugi and Noritaka Hai
American Journal of Psychiatry Vol.162 p810-811.2005

甲状腺刺激ホルモン(TSH)受容体の活性化型変異を同定した自律性機能性甲状腺結節(Autonomous Functioning Thyroid Nodule; AFTN)の本邦第2症例
A second Japanese case with an autonomously functioning thyroid nodule (AFTN) caused by a constitutively activating thyrotropin receptor mutation.
裴紀堯、岡本博臣、玉田愛子、宮武利行、今西幸仁、綿谷正弘、須川秀夫、青木矩彦、森徹、小杉眞司
ホルモンと臨床 特集 内分泌 興味ある症例 第39集59-63項2001年

Familial pulmonary carcinoid tumors.
Oliveira AM, Tazelaar HD, Wentzlaff KA, Kosugi NS, Hai N, Benson A, Miller DL and Yang P.
Cancer
Vol.91 p.2104 - 2109. 2001

原発性副甲状腺機能亢進症(FIHP)と多発性内分泌腺腫症1型(MEN1型)の連続性を示唆する1家系
A family expressing phenotypes between familial isolated primary hyperparathyroidism (FIHP) and multiple endocrine neoplasia type 1 (MEN1)
北脇年雄、裴紀堯、岡本博臣、玉田愛子、米門秀行、木下圭一、横田敏彦、青木矩彦、小杉眞司
ホルモンと臨床 第49巻395-403項2001年

A novel germline mutation of the MEN1 gene, L259del, in a patient with sporadic multiple endocrine neoplasia type 1 (MEN1).
Noritaka Hai, Gen Muto, Hiroomi Okamoto, Aiko Tamada, Ryuzo Abe, Shinichi Suzuki and Shinji Kosugi.
Japanese Journal of Clinical Oncology Vol.31 p.125-127. 2001

末端肥大症・甲状腺乳頭癌・原発性アルドステロン症を合併した多発内分泌腺腫症と考えられる2例
Two suspected cases of multiple endocrine neoplasia consisted of acromegaly, papillary thyroid carcinoma and primary aldosteronism
小林照宗、大村昌夫、堀江篤哉、櫻井健一、石塚俊治、飯塚孝、西川哲男、裴紀堯、青木矩彦、小杉眞司
日本内分泌学会雑誌 第76巻特集号141-143項2000年

MEN-1型に合併する膵内分泌腫瘍の治療方針
Management of pancreatic endocrine tumors associated with multiple endocrine neoplasia type 1 (MEN-1)
土井隆一郎、河本泉、伊丹淳、細谷亮、裴紀堯、小杉眞司、今村正之
臨床雑誌「外科」 第62巻1040-1045項2000年

家族性原発性副甲状腺機能亢進症の一家系
Familial isolated primary hyperparathyroidism: a case report and literature review 紅粉睦男、松田彰、井上篤、伊古田明美、小泉茂樹、真尾泰生、松毛真一、佐々木豊、渡辺一晶、高橋康幸、裴紀堯、小杉眞司
内分泌外科 第17巻105-111項2000年

Gene diagnosis and clinical management of multiple endocrine neoplasia type 1
Noritaka Hai and Shinji Kosugi
Biomedicine and Pharmacotherapy Vol.54 Suppl 1 p.47s-51s. 2000

Clinical features of multiple endocrine neoplasia type 1 (MEN1) phenocopy without germline MEN1 gene mutations: Analysis of 20 Japanese sporadic cases with MEN1
Noritaka Hai, Norihiko Aoki, Akira Shimatsu, Toru Mori and Shinji Kosugi
Clinical Endocrinology (Oxford press) Vol.52 p.509-518. 2000

三姉妹に副腎皮質・髄質腫瘍が認められた1家族例について
A family in which three sisters with adrenal cortical or medullar tumor were identified
野嶋祐兵、小林宏正、日野恵、石原隆、森寺邦三郎、池窪勝治、裴紀堯、小杉眞司、倉八博之
ホルモンと臨床 第48巻169-173項2000年

多発性内分泌腺腫症1型の遺伝子診断とその臨床応用
Genetic diagnosis and clinical management of multiple endocrine adenomatosis type 1
裴紀堯、小杉眞司
遺伝子医学 第4巻139-144項2000年

Germline MEN1 mutations in sixteen Japanese families with multiple endocrine neoplasia type 1 (MEN1)
Noritaka Hai, Norihiko Aoki, Akira Matsuda, Toru Mori and Shinji Kosugi
European Journal of Endocrinology Vol.141 p.475-480. 1999

RET遺伝子コドン634体細胞性点突然変異を認めた散発性甲状腺髄様癌の1例
A case of sporadic medullary carcinoma of the thyroid in which somatic point mutation of the RET gene codon 634
白波瀬功、森徹、古元克好、小杉眞司、裴紀堯、吉崎慎介、三瀬眞一
日本臨床外科学会雑誌 第60巻1197-1204項1999年

Two germline missense mutations at codons 804 and 806 of the RET proto-oncogene in the same allele in a patient with multiple endocrine neoplasia type 2B without codon 918 mutation
Akira Miyauchi, Hitoyasu Futami, Noritaka Hai, Tamotsu Yokozawa, Kanji Kuma, Norihiko Aoki, Shinji Kosugi, Kokichi Sugano and Ken Yamaguchi
Japanese Journal of Cancer Research Vol.90 p.1-5. 1999

Lack of measurable maximal capacity of inorganic iodide pool in non-thyroid cell
Hideo Sugawa, Michiko Ueda, Akira Matsuda, Noritaka Hai, Akio Yoshida and Shinji Kosugi
Thyroidology - clinical and experimental Vol.10 p.297-302. 1998

Recent trends in the management of Graves' hyperthyroidism in Japan: Opinion survey results,especially on the combination therapy of antithyroid drug and thyroid hormone
Toru Mori, Hideo Sugawa, Shinji Kosugi, Michiko Ueda, Noritaka Hai and Akira Matsuda
Endocrine Journal Vol.44 p.509-517. 1997

Aspartate-474 in the first exoplasmic loop of the thyrotropin receptor is crucial for receptor activation
Shinji Kosugi, Akira Matsuda, Noritaka Hai, Norihiko Aoki, Hideo Sugawa and Toru Mori
FEBS Letters Vol. 406 p.139-141. 1997

Establishment and characterization of a Chinese hamster ovary cell line, CHO-4J, stably expressing a number of Na+/I- symporters
Shinji Kosugi, Norihito Sasaki, Noritaka Hai, Hideo Sugawa, Norihiko Aoki, Chiaki Shigemasa, Toru Mori and Akio Yoshida
Biochemical and Biophysical Research Communications Vol.227 p.94-101. 1996

国際学会発表

The complex of acromegaly and primary aldosteronism is not an early clinical feature of multiple endocrine neoplasia type 1
Hai N, Okamoto H, Kobayashi T, Omura M, Nishikawa T, Koyano H, Shimizu H, Taniguchi S, Shigemasa C, Yoshida T, Tatsuno I, Aoki N and Kosugi S
11 th AFES congress; Bali, Indonesia
Journal of the ASEAN Federation of Endocrine Soscieties Vol.20 No.1 p.147. 2002
The Indonesian Society of Endocrinology

Combination of acromegaly, papillary thyroid carcinoma and primary aldosteronism is possibly a new form of MEN
Omura M, Kobayashi T, Saito J, Itou H, Iizuka T, Sasano H, Hai N, Kosugi S and Nishikawa T
11th International Congress of Endocrinology; Sydney, Australia
Abstract Book 2000:167.

Gene diagnosis and clinical management of multiple endocrine neoplasia type 1 (MEN1)
Noritaka Hai, Norihiko Aoki, Akira Matsuda, Akira Shimatsu, Hiroomi Okamoto, Toru Mori and Shinji Kosugi
11th International Congress of Endocrinology; Sydney, Australia
Abstract Book 2000:299.

MEN1 gene diagnosis of one Japanese family with multiple endocrine neoplasia type 1 (MEN1)
Kie Hai, Noritaka Hai, Norihiko Aoki and Shinji Kosugi
11th International Congress of Endocrinology; Sydney, Australia
Abstract Book 2000:319.

Germline de novo mutation of the RET proto-oncogene in a male patient with multiple endocrine neoplasia type 2A
Matsuda A, Beniko M, Koizumi S, Inoue A, Ikota A, Matsuya K, Kunita H, Mashio Y, Hai N and Kosugi S
11th International Congress of Endocrinology; Sydney, Australia
Abstract Book 2000:322.

A second Japanese case with an autonomously functioning thyroid nodule (AFTN) caused by a constitutively activating thyrotropin receptor mutation
Noritaka Hai, Toshiyuki Miyatake, Norihiko Aoki, Yukihito Imanishi, Masahiro Watatani, Hiroomi Okamoto, Hideo Sugawa, Toru Mori and Shinji Kosugi
12th International Thyroid Congress; Kyoto, Japan
Endocrine Journal 2000 Aug;47 Suppl:158.

Clinical features of multiple endocrine neoplasia type 1 (MEN1) phenocopy based on germline MEN1 mutations in the 30 Japanese probands
Noritaka Hai, Norihiko Aoki, Akira Matsuda, Toru Mori and Shinji Kosugi
7th International workshop on multiple endocrine neoplasia; Firenze, Italy
7th International workshop on multiple endocrine neoplasia final program and abstract 1999

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